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TOLUALDEHYDES

Product Name
TOLUALDEHYDES
CAS No.
1334-78-7
Chemical Name
TOLUALDEHYDES
Synonyms
tolyl;TOLUALDEHYDE;TOLUALDEHYDES;ar-Tolualdehyde;METHYLBENZALDEHYDE;tolualdehydes, mixture;TOLUALDEHYDES USP/EP/BP;TOLUALDEHYDES (MIXED O,M,P);TOLUALDEHYDES(MIXEDORTHO,META,PARA)
CBNumber
CB2286866
Molecular Formula
C7H6O
Formula Weight
106.12194
MOL File
1334-78-7.mol
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TOLUALDEHYDES Property

Boiling point:
164.15°C (rough estimate)
Density 
0.9651 (rough estimate)
refractive index 
1.4800 (estimate)
FEMA 
3068 | TOLUALDEHYDES (MIXED O,M,P)
Odor
at 1.00 % in dipropylene glycol. sweet cherry chemical coumarin powdery
Odor Type
fruity
JECFA Number
866
LogP
2.26
EPA Substance Registry System
Methylbenzaldehyde (1334-78-7)
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Safety

Hazardous Substances Data
1334-78-7(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 2250mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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TOLUALDEHYDES Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid. Slightly soluble inwater; soluble in alcohol and ether. There are also oand misomers. Combustible.

Chemical Properties

Tolualdehydes, mixed o-, m-, p-, have a sweet and herbaceous odor reminiscent of bitter almond.

Occurrence

Reported found in roasted nuts, tomato, cooked beef, beef fat, cider, coffee, tea and elderberry juice.

Uses

Perfumes, pharmaceutical and dyestuff intermediate, flavoring agent.

Preparation

By oxidation of o-, m-, or p-xylene (chemical or electrolytical oxidation).

Taste threshold values

Taste characteristics at 15 ppm: cherry pit, coumarin, almond, sweet, with a slight powdery hay and vanillalike nuance.

Metabolism

Aromatic aldehydes are oxidized in vivo almost entirely to the corresponding acid. Thus, in rabbits, p-tolualdehyde is converted to p-toluic acid which has been detected in the urine as the ester glucuronide (Williams, 1959). p-Tolualdehyde was oxidized to p-toluic acid by resting cells of Pseudomonas aeruginosa (Omori & Yamada, 1970). Perillaldehyde dehydrogenase, isolated from a soil pseudomonad, catalysed the oxidation of m- and p-tolualdehyde but not of o-tolualdehyde (Ballal, Bhattacharyya & Rangachari, 1967). The reduction of p-tolualdehyde by NADH was catalysed by horse-liver alcohol dehydrogenase (Blomquist, 1966) and by yeast alcohol dehydrogenase at pH 8.5-9.5 (Klinman, 1975). A non-specific NADPH-linked aldehyde reductase isolated from various areas of bovine brain also catalysed the reduction of p-tolualdehyde (Tabakoff & Erwin, 1970).

TOLUALDEHYDES Preparation Products And Raw materials

Raw materials

Preparation Products

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